Flaten, Gøril Eide; Awoyemi, Opeyemi Linda Ronke; Luthman, Kristina; Brandl, Martin; Massing, Ulrich (Journal article; Tidsskriftartikkel; Peer reviewed, 2009-02)
In-vitro screening for oral absorption has become an essential part of drug discovery and
development. Recently, a new phospholipid vesicle-based permeation assay was
developed which has shown to satisfyingly predict passive absorption of drugs in
humans. The purpose of the current study was to investigate whether the assay may be
further developed into a high-throughput tool by automating its ...